KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK9
All Species:
34.24
Human Site:
Y287
Identified Species:
50.22
UniProt:
P50750
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50750
NP_001252.1
372
42778
Y287
K
A
Y
V
R
D
P
Y
A
L
D
L
I
D
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094502
352
40482
Y267
K
A
Y
V
R
D
P
Y
A
L
D
L
I
D
K
Dog
Lupus familis
XP_548446
534
59045
Y449
K
A
Y
V
R
D
P
Y
A
L
D
L
I
D
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_570930
372
42743
Y287
K
A
Y
V
R
D
P
Y
A
L
D
L
I
D
K
Rat
Rattus norvegicus
Q641Z4
372
42743
Y287
K
A
Y
V
R
D
P
Y
A
L
D
L
I
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520593
314
36161
I234
D
P
Y
A
L
D
L
I
D
K
L
L
V
L
D
Chicken
Gallus gallus
Q5ZKN1
372
42784
Y287
K
A
Y
V
K
D
P
Y
A
L
D
L
I
D
K
Frog
Xenopus laevis
Q4V862
376
43205
H291
K
A
Y
V
K
D
P
H
A
L
D
L
I
D
K
Zebra Danio
Brachydanio rerio
NP_997756
393
45129
Y309
K
A
Y
V
K
D
P
Y
A
L
D
L
I
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477226
404
46768
T319
R
P
Y
V
K
D
Q
T
G
C
D
L
L
D
K
Honey Bee
Apis mellifera
XP_396015
382
43973
Y293
K
P
Y
L
K
D
P
Y
A
C
D
L
L
D
K
Nematode Worm
Caenorhab. elegans
Q9TVL3
478
53575
A363
K
N
L
M
K
F
D
A
P
D
S
K
T
D
P
Sea Urchin
Strong. purpuratus
XP_798269
410
46418
Q316
R
S
Y
V
K
D
Q
Q
A
L
D
L
I
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
H297
F
F
R
H
F
D
R
H
A
L
E
L
L
E
K
Baker's Yeast
Sacchar. cerevisiae
P23293
657
74221
G339
G
K
Y
L
S
E
T
G
L
D
F
L
G
Q
L
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
P298
R
R
F
E
K
H
G
P
V
V
I
S
L
L
K
Conservation
Percent
Protein Identity:
100
N.A.
92.4
68.5
N.A.
98.6
98.6
N.A.
77.9
93
89.3
85.5
N.A.
66
72.7
43.3
67.3
Protein Similarity:
100
N.A.
93.5
69.4
N.A.
99.7
99.7
N.A.
80.3
95.4
94.1
89.5
N.A.
75.9
83.2
56.4
75.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
93.3
86.6
93.3
N.A.
46.6
66.6
13.3
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
66.6
86.6
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
25.2
31.7
Protein Similarity:
N.A.
N.A.
N.A.
51
39.4
45.6
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
7
0
0
0
7
69
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
82
7
0
7
13
69
0
0
75
7
% D
% Glu:
0
0
0
7
0
7
0
0
0
0
7
0
0
7
0
% E
% Phe:
7
7
7
0
7
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
7
7
7
0
0
0
7
0
0
% G
% His:
0
0
0
7
0
7
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
7
0
57
0
0
% I
% Lys:
63
7
0
0
50
0
0
0
0
7
0
7
0
0
82
% K
% Leu:
0
0
7
13
7
0
7
0
7
63
7
88
25
13
7
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
19
0
0
0
0
57
7
7
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
13
7
0
0
0
0
0
7
0
% Q
% Arg:
19
7
7
0
32
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
7
0
0
0
0
0
7
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
7
0
0
0
0
7
0
0
% T
% Val:
0
0
0
63
0
0
0
0
7
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
82
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _